SCHEMBL28574237

SCHEMBL28574237

Clc1ccc(C23C4C5C6C4C2C6C53)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.40
MAOB P27338 2/20 0.40
LMNA P02545 1/20 0.40
CYP2A6 P11509 1/20 0.40
KDM1A O60341 1/20 0.40
HSD11B1 P28845 2/20 0.33
DRD2 P14416 1/20 0.33
SLC6A4 P31645 3/20 0.32
SLC6A3 Q01959 3/20 0.32
IDO1 P14902 1/20 0.32
CHRNA1 P02708 1/20 0.30
CHRNG P07510 1/20 0.30
CHRNB1 P11230 1/20 0.30
CHRNB2 P17787 1/20 0.30
SLC6A2 P23975 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
CHRND Q07001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20540884 0.67 HSD11B1 (0.46) HSD11B1
1,4-Dichlorobenzene SCHEMBL11243685 0.63
1,4-Dichlorobenzene SCHEMBL5191 0.63
SCHEMBL25405882 0.63 CES2 (0.46) LMNA
SCHEMBL25404658 0.63 ADRB2 (0.43) MAOAMAOBLMNACYP2A6SLC6A4
SCHEMBL11786907 0.62 MAOA (0.52) MAOAMAOBLMNACYP2A6KDM1A
SCHEMBL10362472 0.60 SLC6A3 (0.41) MAOAMAOBLMNACYP2A6KDM1A
SCHEMBL4778396 0.60 LMNA (0.40) MAOAMAOBLMNACYP2A6KDM1A
SCHEMBL9735920 0.60 CCNB2 (0.47) MAOAMAOBLMNACYP2A6KDM1A
1,4-Dichlorobenzene SCHEMBL10603593 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112955437-A Compounds useful in organic electronic devices 默克专利有限公司 2021-06-11 CN disclosed