Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19904701 | 1.00 | DPP4 (0.42) | DPP4DRD2DRD4DRD3LMNA | |
| SCHEMBL5503597 | 0.89 | LMNA (0.45) | DPP4LMNASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL11677163 | 0.87 | LMNA (0.43) | DPP4LMNASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL11553081 | 0.87 | LMNA (0.43) | DPP4LMNASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL17528777 | 0.84 | LTA4H (0.41) | LMNATSHRHPGDALDH1A1SLC6A2 | |
| SCHEMBL8648037 | 0.79 | LTA4H (0.45) | LMNATSHRL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL10860055 | 0.79 | LTA4H (0.45) | LMNATSHRL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL13289 | 0.79 | LTA4H (0.50) | LMNATSHRL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL7937629 | 0.78 | LMNA (0.41) | LMNASMN1; SMN2TSHRL3MBTL1MAPT | |
| SCHEMBL17528779 | 0.78 | LTA4H (0.36) | LMNASMN1; SMN2TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306094-B1 | PROCESS FOR THE HYDROFORMYLATION OF CERTAIN ACRYLIC ACID DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-01-29 | — | — | EP | disclosed |
| EP-0306094-A2 | Process for the hydroformylation of certain acrylic acid derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-03-08 | — | — | EP | disclosed |