Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5503597 | 0.88 | LMNA (0.45) | LMNASMN1; SMN2TSHRHPGDSLC6A4 | |
| SCHEMBL11553081 | 0.86 | LMNA (0.43) | LMNASMN1; SMN2TSHRHPGDSLC6A4 | |
| SCHEMBL11677163 | 0.86 | LMNA (0.43) | LMNASMN1; SMN2TSHRHPGDSLC6A4 | |
| SCHEMBL19904678 | 0.80 | L3MBTL1 (0.42) | LMNASMN1; SMN2TSHRHPGDSLC6A4 | |
| SCHEMBL19904701 | 0.78 | DPP4 (0.42) | LMNASMN1; SMN2TSHRHPGDSLC6A4 | |
| SCHEMBL9621279 | 0.78 | DPP4 (0.42) | LMNASMN1; SMN2TSHRHPGDSLC6A4 | |
| SCHEMBL7602939 | 0.76 | LMNA (0.43) | LMNASMN1; SMN2TSHRHPGDSLC6A4 | |
| SCHEMBL3888515 | 0.76 | TSHR (0.41) | SMN1; SMN2TSHRHPGDSLC6A4SLC6A2 | |
| SCHEMBL5503600 | 0.74 | LMNA (0.42) | LMNASMN1; SMN2TSHRHPGDSLC6A4 | |
| SCHEMBL1364726 | 0.74 | LMNA (0.42) | LMNASMN1; SMN2TSHRHPGDSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248916-B1 | WATER SOLUBLE, STRAIGHT CHAIN BORON-RICH OLIGOPHOSPHATE WHICH COMPRISES AN ORDERED PLURALITY OF CARBORANE MONOMER UNITS HAVING TWO HYDROXYL GROUPS ATTACHED THERETO BEING LINKED BY THE HYDROXYL GROUPS TO PHOSPHATE UNITS | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-06-19 | — | — | US | disclosed |
| US-5856551-A | REACTING DIHYDROXYCARBORANE WITH PHOSPHORUS COUPLING AGENT;THEN ALCOHOL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-01-05 | — | — | US | disclosed |
| WO-1995026359-A1 | MACROMOLECULAR STRUCTURES FOR BORON NEUTRON-CAPTURE THERAPY | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-10-05 | — | — | WO | disclosed |