Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621831 | 0.84 | ALDH1A1 (0.37) | NPC1RAB9ALMNAKMT2AKDM4E | |
| SCHEMBL7081592 | 0.82 | NPC1 (0.56) | NPC1RAB9ALMNAKMT2AKDM4E | |
| SCHEMBL9179117 | 0.76 | NPC1 (0.42) | NPC1RAB9ALMNATSHRPOLB | |
| SCHEMBL11729209 | 0.73 | RAB9A (0.47) | NPC1RAB9ALMNAKMT2AKDM4E | |
| SCHEMBL9460248 | 0.72 | NPC1 (0.48) | NPC1RAB9ALMNAKMT2AKDM4E | |
| SCHEMBL9178544 | 0.70 | SMN1; SMN2 (0.41) | NPC1RAB9ALMNAKMT2ATSHR | |
| SCHEMBL9180997 | 0.69 | NPC1 (0.43) | NPC1RAB9ALMNAKMT2AKDM4E | |
| SCHEMBL11345397 | 0.69 | NPC1 (0.62) | NPC1RAB9ALMNAKMT2AKDM4E | |
| SCHEMBL3285209 | 0.68 | NPC1 (0.65) | NPC1RAB9AKMT2AKDM4ETSHR | |
| SCHEMBL11881991 | 0.68 | LMNA (0.48) | NPC1RAB9ALMNAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263905-B1 | METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |
| EP-0259530-B1 | METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES | CHEMIPRO KASEI KAISHA LTD (JP) | 1992-04-08 | — | — | EP | disclosed |
| EP-0263905-A1 | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1988-04-20 | — | — | EP | disclosed |
| EP-0259530-A1 | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1988-03-16 | — | — | EP | disclosed |