Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621689 | 0.84 | NPC1 (0.42) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL7081592 | 0.66 | NPC1 (0.56) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL11881991 | 0.64 | LMNA (0.48) | HSD17B10NPC1RAB9ALMNAKMT2A | |
| SCHEMBL3285898 | 0.64 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EHSD17B10NPC1 | |
| SCHEMBL9327385 | 0.63 | GABRA1 (0.50) | ALDH1A1HPGDLMNAKMT2AMEN1 | |
| SCHEMBL9179117 | 0.61 | NPC1 (0.42) | NPC1RAB9ALMNA | |
| SCHEMBL9460248 | 0.61 | NPC1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10NPC1 | |
| SCHEMBL11345397 | 0.60 | NPC1 (0.62) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL28490762 | 0.60 | LMNA (0.50) | ALDH1A1HPGDHSD17B10LMNAKMT2A | |
| SCHEMBL10484328 | 0.60 | NPC1 (0.55) | ALDH1A1HPGDKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263905-B1 | METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |
| EP-0259530-B1 | METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES | CHEMIPRO KASEI KAISHA LTD (JP) | 1992-04-08 | — | — | EP | disclosed |
| EP-0263905-A1 | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1988-04-20 | — | — | EP | disclosed |
| EP-0259530-A1 | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1988-03-16 | — | — | EP | disclosed |