Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911825 | 0.86 | HDAC1 (0.56) | L3MBTL1HPGDMEN1KMT2AHDAC1 | |
| SCHEMBL4055883 | 0.85 | L3MBTL1 (0.61) | L3MBTL1MTNR1AMTNR1BHPGDMEN1 | |
| SCHEMBL10361230 | 0.85 | KCNA3 (0.62) | L3MBTL1HPGDMEN1KMT2AHDAC1 | |
| SCHEMBL17002035 | 0.82 | RECQL (0.58) | L3MBTL1HPGDMEN1KMT2AHDAC1 | |
| SCHEMBL15178062 | 0.81 | LTA4H (0.55) | L3MBTL1HPGDMEN1KMT2AHDAC1 | |
| SCHEMBL15061644 | 0.80 | HDAC1 (0.62) | L3MBTL1MTNR1AMTNR1BHDAC1HDAC2 | |
| SCHEMBL2222064 | 0.80 | ALOX15 (0.59) | L3MBTL1MTNR1AMTNR1BHPGDMEN1 | |
| SCHEMBL8278956 | 0.80 | MTNR1A (0.59) | L3MBTL1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL10804736 | 0.79 | L3MBTL1 (0.58) | L3MBTL1MTNR1AMTNR1BHDAC1HDAC2 | |
| SCHEMBL9153257 | 0.79 | EPHX2 (0.46) | L3MBTL1SMN1; SMN2TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307358-B1 | 1,3-DIKETONES CONTAINING ETHERS OR THIOETHERS AND THEIR USE AS STABILISING AGENTS IN CHLORINATED POLYMERS | CIBA-GEIGY AG (CH) | 1992-02-12 | — | — | EP | claimed |
| US-4992504-A | Heat resistance, photostability | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | claimed |
| EP-0307358-B1 | 1,3-DIKETONES CONTAINING ETHERS OR THIOETHERS AND THEIR USE AS STABILISING AGENTS IN CHLORINATED POLYMERS | CIBA-GEIGY AG (CH) | 1992-02-12 | — | — | EP | disclosed |
| US-4992504-A | Heat resistance, photostability | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0307358-A1 | 1,3-Diketones containing ethers or thioethers and their use as stabilising agents in chlorinated polymers | CIBA-GEIGY AG (CH) | 1989-03-15 | — | — | EP | disclosed |