Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.64 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.64 |
| ▸ | CCR2 | P41597 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858374 | 0.87 | NOD2 (0.80) | NOD2NOD1CCR2MAPTALDH1A1 | |
| SCHEMBL5093926 | 0.87 | CCR9 (0.64) | NOD2NOD1CCR2MAPTALDH1A1 | |
| SCHEMBL9536869 | 0.87 | CCR2 (0.76) | CCR2MAPTALDH1A1POLBPTGS2 | |
| SCHEMBL1503984 | 0.86 | NOD2 (0.67) | NOD2NOD1CCR2MAPTALDH1A1 | |
| SCHEMBL3578136 | 0.85 | PPARG (0.54) | NOD2NOD1CCR2MAPTF10 | |
| SCHEMBL4798323 | 0.85 | NOD2 (0.85) | NOD2NOD1CCR2MAPTALDH1A1 | |
| SCHEMBL4414074 | 0.85 | NOD2 (0.65) | NOD2NOD1CCR2MAPTALDH1A1 | |
| SCHEMBL15642607 | 0.84 | NOD2 (0.58) | NOD2NOD1CCR2MAPTALDH1A1 | |
| SCHEMBL6867612 | 0.83 | CCR2 (0.61) | NOD2NOD1CCR2MAPTALDH1A1 | |
| SCHEMBL4051157 | 0.83 | L3MBTL1 (0.53) | NOD2NOD1CCR2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |