Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622599 | 1.00 | LMNA (0.44) | LMNASMN1; SMN2ADRA2CADRA2BSLC6A3 | |
| SCHEMBL9367286 | 0.90 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2HTR2AHTR2CHTR2B | |
| SCHEMBL9367280 | 0.90 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2HTR2AHTR2CHTR2B | |
| Fumaric Acid SCHEMBL9622178 | 0.84 | ALDH1A1 (0.49) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| Fumaric Acid SCHEMBL9622181 | 0.84 | ALDH1A1 (0.49) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| Fumaric Acid SCHEMBL9622176 | 0.84 | ALDH1A1 (0.49) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL9622908 | 0.76 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2ADRA2CADRA2BDRD2 | |
| SCHEMBL9622905 | 0.76 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2ADRA2CADRA2BDRD2 | |
| SCHEMBL9622848 | 0.75 | CHRM2 (0.45) | LMNASMN1; SMN2ADRA2CADRA2BSLC6A3 | |
| SCHEMBL9622236 | 0.74 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2OPRM1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126356-A | Antiischemic agents | ADIR ET COMPAGNIE (FR) | 1992-06-30 | — | — | US | disclosed |