Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622848 | 0.80 | CHRM2 (0.45) | CYP2C19POLBMEN1KMT2AKDM4E | |
| SCHEMBL30573474 | 0.77 | CYP2C19 (0.67) | ALDH1A1CYP2C19POLBPKMMEN1 | |
| SCHEMBL9622210 | 0.74 | CYP1A2 (0.52) | POLBMEN1KMT2ASMN1; SMN2 | |
| Fumaric Acid SCHEMBL9622178 | 0.71 | ALDH1A1 (0.49) | ALDH1A1CYP2C19MAPTMEN1KMT2A | |
| Fumaric Acid SCHEMBL9622181 | 0.71 | ALDH1A1 (0.49) | ALDH1A1CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL9622306 | 0.70 | ALOX5 (0.47) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9366603 | 0.70 | CPT1B (0.55) | ALDH1A1POLBMAPTPKMMEN1 | |
| SCHEMBL9367280 | 0.70 | SMN1; SMN2 (0.48) | ALDH1A1CYP2C19MAPTPKMMEN1 | |
| SCHEMBL9367286 | 0.70 | SMN1; SMN2 (0.48) | ALDH1A1CYP2C19MAPTPKMMEN1 | |
| SCHEMBL3545519 | 0.68 | MEN1 (0.58) | ALDH1A1CYP2C19POLBPDE4BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126356-A | Antiischemic agents | ADIR ET COMPAGNIE (FR) | 1992-06-30 | — | — | US | disclosed |