Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | QRFPR | Q96P65 | 9/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622848 | 0.82 | CHRM2 (0.45) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 | |
| SCHEMBL27549083 | 0.78 | SLC6A4 (0.56) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 | |
| SCHEMBL9622896 | 0.74 | ALDH1A1 (0.46) | POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9367286 | 0.71 | SMN1; SMN2 (0.48) | CYP1A2HTR2CSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9367280 | 0.71 | SMN1; SMN2 (0.48) | CYP1A2HTR2CSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8307284 | 0.70 | TDP1 (0.50) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9622597 | 0.69 | LMNA (0.44) | CHRM2SLC6A4OPRK1HTR2CSMN1; SMN2 | |
| Trimetazidine SCHEMBL29375563 | 0.69 | CHRM2 (1.00) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 | |
| Trimetazidine SCHEMBL230374 | 0.69 | CHRM2 (1.00) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 | |
| Trimetazidine SCHEMBL11846840 | 0.69 | CHRM2 (1.00) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126356-A | Antiischemic agents | ADIR ET COMPAGNIE (FR) | 1992-06-30 | — | — | US | disclosed |