Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 5/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623046 | 0.82 | HTR3A (0.47) | MEN1CYP2C9CYP2C19KMT2ADRD3 | |
| SCHEMBL9622424 | 0.81 | HTR3A (0.58) | MEN1CYP2C9CYP2C19KMT2ADRD2 | |
| SCHEMBL9623137 | 0.81 | DRD2 (0.44) | MEN1CYP2C9CYP2C19KMT2ADRD2 | |
| SCHEMBL9623235 | 0.79 | DRD2 (0.45) | MEN1CYP2C9CYP2C19KMT2ADRD3 | |
| SCHEMBL9622705 | 0.79 | DRD2 (0.44) | MEN1CYP2C9CYP2C19KMT2ADRD3 | |
| SCHEMBL9622432 | 0.78 | DRD2 (0.49) | MEN1CYP2C9CYP2C19KMT2ALMNA | |
| SCHEMBL9622821 | 0.77 | HTR4 (0.40) | MEN1CYP2C9CYP2C19KMT2ADRD3 | |
| SCHEMBL9622761 | 0.77 | PRKAB2 (0.43) | KMT2AHTR4 | |
| Fumaric Acid SCHEMBL9622753 | 0.77 | CYP3A4 (0.46) | MEN1CYP2C9CYP2C19KMT2ACYP3A4 | |
| Fumaric Acid SCHEMBL9622764 | 0.77 | CYP3A4 (0.46) | MEN1CYP2C9CYP2C19KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137895-A | Antiemetic, anxiolytic, gastric emptying and serotonin modulating activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-08-11 | — | — | US | disclosed |