Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92880 | 0.97 | CYP1A2 (0.37) | ALDH1A1ATMCYP1A2ACHEADH1B | |
| SCHEMBL4939644 | 0.94 | — | — | |
| SCHEMBL1272565 | 0.88 | — | — | |
| SCHEMBL12424348 | 0.83 | JAK2 (0.33) | JAK2JAK1TYK2JAK3SMO | |
| SCHEMBL18289302 | 0.80 | INPP5A (0.32) | ACHE | |
| SCHEMBL15014541 | 0.79 | KDM4E (0.32) | ALDH1A1ACHEJAK2JAK1TYK2 | |
| SCHEMBL14708341 | 0.79 | KDM4E (0.32) | ALDH1A1ACHEJAK2JAK1TYK2 | |
| SCHEMBL12821866 | 0.78 | INPP5A (0.32) | ACHE | |
| SCHEMBL12821856 | 0.78 | INPP5A (0.32) | ACHE | |
| SCHEMBL12821857 | 0.78 | INPP5A (0.32) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067215-A1 | PIPERIDINE COMPOUNDS AS MENIN INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2021-04-08 | — | — | WO | disclosed |
| EP-3347097-B1 | SUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS MODULATORS OF THE KINASES JAK, FLT3 AND AURORA | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-02-24 | — | — | EP | disclosed |
| WO-2020072391-A1 | SMALL MOLECULE MENIN INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-04-09 | — | — | WO | disclosed |
| WO-2019191526-A1 | PIPERIDINE COMPOUNDS AS COVALENT MENIN INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-10-03 | — | — | WO | disclosed |
| US-20180022752-A1 | FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2018-01-25 | — | — | US | disclosed |
| WO-2017044434-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-03-16 | — | — | WO | disclosed |
| US-20170073334-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-03-16 | — | — | US | disclosed |
| US-8927458-B2 | Herbicide triazolylpyridine ketones | BAYER CROPSCIENCE AG (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8927458-B2 | Herbicide triazolylpyridine ketones | BAYER CROPSCIENCE AG (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8658798-B2 | Herbicide triazolylpyridine ketones | BAYER CROPSCIENCE AG (DE) | 2014-02-25 | — | — | US | disclosed |
| US-20130296168-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2013-11-07 | — | — | US | disclosed |
| US-8309196-B2 | Optical recording medium, optical recording material and metal complex compound | MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) | 2012-11-13 | — | — | US | disclosed |
| US-8129428-B2 | Insecticidal carbamates exhibiting species-selective inhibition of acetylcholinesterase (AChE) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110311752-A1 | OPTICAL RECORDING MEDIUM, OPTICAL RECORDING MATERIAL AND METAL COMPLEX COMPOUND | MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) | 2011-12-22 | — | — | US | disclosed |
| US-20110237800-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| US-20110237800-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| US-20110069595-A1 | AZO METAL CHELATE DYE AND OPTICAL RECORDING MEDIUM | MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) | 2011-03-24 | — | — | US | disclosed |
| US-20090068242-A1 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2009-03-12 | — | — | US | disclosed |
| US-20050250822-A1 | Substituted benzanilide compound and noxious organism controlling agent | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-11-10 | — | — | US | disclosed |
| EP-1538138-A1 | SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2005-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073334-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | PRKACA, PRKDC, PRKACB | ALDH1A1 4070/4885ATM 851/4885CYP1A2 1829/4885 |
| US-20130296168-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | DDT, PDK4, BCKDK | ALDH1A1 43/4885ATM 3469/4885CYP1A2 54/4885 |
| US-20110237800-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | DDT, PDK4, BCKDK | ALDH1A1 56/4885ATM 3359/4885CYP1A2 68/4885 |
| US-20180022752-A1 | FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF | IDO1, IDO2, TDO2 | ALDH1A1 2128/4885ATM 3981/4885CYP1A2 116/4885 |
| US-20090068242-A1 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) | ACHE, BCHE, CHAT | ALDH1A1 960/4885ATM 3160/4885CYP1A2 78/4885 |
| US-20050250822-A1 | Substituted benzanilide compound and noxious organism controlling agent | GCN1, L3MBTL3, L3MBTL4 | ALDH1A1 1987/4885ATM 2582/4885CYP1A2 693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.