Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | KLK1 | P06870 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 9/20 | 0.49 |
| ▸ | THRA | P10827 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623582 | 0.88 | TPMT (0.45) | TPMTTTRPLAUKLK1THRB | |
| SCHEMBL1458048 | 0.84 | THRB (0.64) | TPMTTTRTHRBTHRAKMT2A | |
| SCHEMBL6841007 | 0.81 | TPMT (0.45) | TPMTTTRPLAUKLK1THRB | |
| SCHEMBL13915098 | 0.79 | KDM4E (0.56) | KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9623323 | 0.79 | PLAU (0.79) | TPMTTTRPLAUTHRBTHRA | |
| SCHEMBL29108936 | 0.78 | THRA (0.66) | THRBTHRAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3546802 | 0.77 | TPMT (0.79) | TPMTTTRTHRBTHRAKMT2A | |
| SCHEMBL9623929 | 0.75 | PLAU (0.53) | TTRPLAUKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9622975 | 0.75 | PLAU (0.49) | TPMTPLAUTHRBTHRAKMT2A | |
| SCHEMBL9622873 | 0.75 | F2 (0.56) | TPMTPLAUTHRBTHRAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212944-B1 | MELT-PROCESSABLE AROMATIC COPOLYESTER | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4746721-A | ENGINEERING PLASTICS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1988-05-24 | — | — | US | disclosed |
| EP-0212944-A2 | Melt-processable aromatic copolyester | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1987-03-04 | — | — | EP | disclosed |