Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.37 |
| ▸ | PGR | P06401 | 4/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623997 | 0.87 | ABCB11 (0.36) | NR3C1PGRARNR3C2ABCB11 | |
| SCHEMBL9623691 | 0.82 | NR3C1 (0.39) | NR3C1PGRARNR3C2ABCB11 | |
| SCHEMBL9623719 | 0.80 | NR3C1 (0.32) | NR3C1 | |
| SCHEMBL8746775 | 0.80 | NR3C1 (0.35) | NR3C1PGRARNR3C2ABCB11 | |
| SCHEMBL9624125 | 0.76 | CYP19A1 (0.56) | CYP19A1 | |
| SCHEMBL8940232 | 0.74 | NR3C1 (0.60) | NR3C1PGRARNR3C2CYP19A1 | |
| SCHEMBL9623805 | 0.74 | NR3C1 (0.60) | NR3C1PGRARNR3C2CYP19A1 | |
| SCHEMBL9623817 | 0.73 | NR3C1 (0.42) | NR3C1PGRARNR3C2ABCB11 | |
| SCHEMBL9623653 | 0.72 | NR3C1 (0.42) | NR3C1PGRARNR3C2ABCB11 | |
| SCHEMBL9623858 | 0.72 | NR3C1 (0.35) | NR3C1PGRARNR3C2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | disclosed |
| US-4977255-A | Steroidal 17α-silyl ethers and process to corticoids and progesterones | THE UPJOHN COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4921638-A | 17β-cyano-9α,17α-dihydroxyandrost-4-en-3-one | THE UPJOHN COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0334875-A1 | STEROIDAL 17$g(a)-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES | THE UPJOHN COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |
| EP-0268400-A1 | Steroidal 17alpha-silyl ethers and process to corticoids and progesterones | THE UPJOHN COMPANY (US) | 1988-05-25 | — | — | EP | disclosed |
| WO-1988003534-A1 | STEROIDAL 17alpha-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES | THE UPJOHN COMPANY (US) | 1988-05-19 | — | — | WO | disclosed |