Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623680 | 0.87 | NR3C1 (0.37) | ABCB11NR3C1ARPGRNR3C2 | |
| SCHEMBL9623603 | 0.81 | ABCB11 (0.38) | ABCB11NR3C1ARPGRNR3C2 | |
| SCHEMBL8746775 | 0.74 | NR3C1 (0.35) | ABCB11NR3C1ARPGRNR3C2 | |
| SCHEMBL9623817 | 0.73 | NR3C1 (0.42) | ABCB11NR3C1ARPGRNR3C2 | |
| SCHEMBL9623872 | 0.73 | NR3C1 (0.45) | ABCB11NR3C1ARPGRNR3C2 | |
| SCHEMBL9623805 | 0.72 | NR3C1 (0.60) | NR3C1ARPGRNR3C2ESR1 | |
| SCHEMBL8940232 | 0.72 | NR3C1 (0.60) | NR3C1ARPGRNR3C2ESR1 | |
| SCHEMBL9624281 | 0.71 | NR3C1 (0.43) | ABCB11NR3C1ARPGRNR3C2 | |
| SCHEMBL9623691 | 0.70 | NR3C1 (0.39) | ABCB11NR3C1ARPGRNR3C2 | |
| SCHEMBL9622893 | 0.70 | NR3C1 (0.41) | ABCB11NR3C1ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |