Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624815 | 0.90 | KDM4E (0.45) | RAB9ASMN1; SMN2HTR2AMAPTNPC1 | |
| SCHEMBL9624653 | 0.90 | LMNA (0.46) | RAB9AHTR1ASMN1; SMN2HTR2AHTR2C | |
| SCHEMBL9624812 | 0.88 | SLC6A4 (0.45) | HTR1AHTR2AHTR2CHTR2BMAPT | |
| SCHEMBL9624308 | 0.87 | HTR1A (0.48) | RAB9AHTR1ASMN1; SMN2HTR2AHTR2C | |
| SCHEMBL9624696 | 0.85 | HTR1D (0.53) | MAPTMEN1KMT2ASLC6A4KDM4E | |
| SCHEMBL9625216 | 0.84 | TACR2 (0.41) | BCHERAB9AHTR1ASMN1; SMN2HTR2A | |
| SCHEMBL9624805 | 0.83 | SIGMAR1 (0.38) | RAB9AHTR1ASMN1; SMN2HTR2AMAPT | |
| SCHEMBL9624315 | 0.82 | ALOX15 (0.36) | RAB9AHTR1ASMN1; SMN2HTR2AMAPT | |
| SCHEMBL10651047 | 0.80 | HCN4 (0.50) | BCHERAB9AHTR1ASMN1; SMN2HTR2A | |
| SCHEMBL9623773 | 0.80 | BCHE (0.46) | BCHERAB9AHTR1ASMN1; SMN2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116986-A | HETEROAROMATIC AMINE DERIVATIVES | DR. KARL THOMAE GMBH (DE) | 1992-05-26 | — | — | US | disclosed |
| US-4912115-A | Cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1990-03-27 | — | — | US | disclosed |