SCHEMBL9624573

SCHEMBL9624573

CCCCC(CC(=O)Cl)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.40
FDPS P14324 1/20 0.38
TSHR P16473 2/20 0.38
CA2 P00918 3/20 0.36
CA1 P00915 2/20 0.36
FAAH O00519 8/20 0.35
MAPK1 P28482 1/20 0.35
CTSL P07711 1/20 0.35
CTSS P25774 1/20 0.35
CTSK P43235 1/20 0.35
CES1 P23141 5/20 0.34
CES2 O00748 2/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8433897 0.82 GPR84 (0.46) FDPSCA2CA1FAAHMAPK1
Hydrochloric Acid SCHEMBL9624578 0.81 GPR84 (0.44) FDPSCA2CA1FAAHMAPK1
SCHEMBL9419145 0.78 CA1 (0.42) ALDH1A1FDPSTSHRCA2CA1
SCHEMBL31676680 0.78 TSHR (0.32) ALDH1A1TP53TSHR
SCHEMBL1987290 0.78 FDPS (0.41) ALDH1A1FDPSCA2CA1FAAH
SCHEMBL22161805 0.76 FDPS (0.40) ALDH1A1FDPSTSHRCA2CA1
SCHEMBL8433717 0.76 GPR84 (0.56) ALDH1A1FDPSTSHR
SCHEMBL9636337 0.74 ALDH1A1 (0.44) ALDH1A1TP53FDPSTSHRCA2
SCHEMBL9636343 0.74 ALDH1A1 (0.44) ALDH1A1TP53FDPSTSHRCA2
SCHEMBL9624831 0.73 AKR1B1 (0.45) ALDH1A1TSHRMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0301511-B1 OPTICALLY ACTIVE COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME CANON KABUSHIKI KAISHA (JP) 1992-01-22 EP disclosed
US-5073306-A Trifluoromethylalkyl substituted CANON KABUSHIKI KAISHA (JP) 1991-12-17 US disclosed
US-4918213-A HAVING A TRIFLUOROMETHYL GROUP ATTACHED TO ASYMMETRIC CARBON ATOM; STABLE; OPTICAL DEVICES CANON KABUSHIKI KAISHA (JP) 1990-04-17 US disclosed
EP-0301511-A1 Optically active compound and liquid crystal composition containing same CANON KABUSHIKI KAISHA (JP) 1989-02-01 EP disclosed