SCHEMBL9624769

SCHEMBL9624769

Oc1cccc2c[c]sc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.38
CA2 P00918 3/20 0.38
ALDH1A1 P00352 5/20 0.35
MEN1 O00255 1/20 0.35
DNMT1 P26358 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
KMT2A Q03164 1/20 0.35
MCL1 Q07820 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
ALOX15 P16050 4/20 0.35
HPGD P15428 4/20 0.35
HSD17B10 Q99714 4/20 0.35
LMNA P02545 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
MMP2 P08253 2/20 0.35
EGFR P00533 2/20 0.35
FYN P06241 2/20 0.35
MMP9 P14780 2/20 0.35
RECQL P46063 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5536780 0.76 PSMB8 (0.34) CA12
SCHEMBL445707 0.74 CA12 (0.31) CA12
SCHEMBL533360 0.74 CYP1A2 (0.38) CYP1A2ALDH1A1LMNATSHRHDAC8
SCHEMBL20562770 0.72 NR4A1 (0.46) CA2ALDH1A1ALOX15HPGDHSD17B10
SCHEMBL533694 0.71 CA2 (0.41) CA2ALDH1A1KMT2AALOX15HPGD
SCHEMBL5865972 0.70 ALDH1A1 (0.46) CYP1A2ALDH1A1HPGDHSD17B10TDP1
SCHEMBL16289874 0.69 CA1 (0.39) CYP1A2CA2ALDH1A1CA1TSHR
SCHEMBL16289528 0.69 ALDH1A1 (0.33) ALDH1A1
SCHEMBL21295664 0.69 ALDH1A1 (0.39) ALDH1A1MEN1KMT2AMCL1HPGD
SCHEMBL693660 0.69 HDAC3 (0.41) ALDH1A1MEN1KMT2AHDAC8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
CN-104955332-B The method of preventing and treating arthropod insect 住友化学株式会社 2017-03-29 CN disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
CN-104955332-A Method for controlling arthropod pest SUMITOMO CHEMICAL CO 2015-09-30 CN disclosed
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-01 US disclosed
EP-2813492-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL Sumitomo Chemical Co., Ltd (JP) 2014-12-17 EP disclosed
US-5175157-A Cardiovascular disorders BOEHRINGER INGELHEIM GMBH (DE) 1992-12-29 US disclosed
US-5116986-A HETEROAROMATIC AMINE DERIVATIVES DR. KARL THOMAE GMBH (DE) 1992-05-26 US disclosed
US-4912115-A Cardiovascular disorders DR. KARL THOMAE GMBH (DE) 1990-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 CYP1A2 193/4885CA2 1119/4885ALDH1A1 3053/4885
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL RPS8, MT-CO2, ARG1 CYP1A2 355/4885CA2 1763/4885ALDH1A1 3265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.