Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129013 | 0.88 | SIRT1 (0.65) | TDP1ATML3MBTL1SIRT1HPGD | |
| SCHEMBL26068033 | 0.86 | SLC6A9 (0.48) | TDP1ATML3MBTL1SIRT1HSD17B10 | |
| SCHEMBL9625444 | 0.85 | SIRT1 (0.56) | TDP1ATML3MBTL1SIRT1HPGD | |
| SCHEMBL29363502 | 0.83 | ATM (0.65) | TDP1ATML3MBTL1HSD17B10HPGD | |
| SCHEMBL5317255 | 0.83 | ATM (0.65) | TDP1ATML3MBTL1HSD17B10HPGD | |
| SCHEMBL9625706 | 0.82 | AKR1C3 (0.59) | TDP1ATML3MBTL1SIRT1CYP2C9 | |
| SCHEMBL1447741 | 0.82 | KDM4E (0.59) | TDP1SIRT1HSD17B10HPGDCYP1A2 | |
| SCHEMBL1127672 | 0.81 | SIRT1 (0.56) | TDP1ATML3MBTL1SIRT1HPGD | |
| Acetophenone SCHEMBL28395442 | 0.81 | ALDH1A1 (0.59) | TDP1L3MBTL1SIRT1HPGDAKR1C3 | |
| SCHEMBL14653057 | 0.80 | SRD5A2 (0.54) | SIRT1POLBMAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279217-B1 | PROCESS FOR THE PREPARATION OF POLY(ARYLENSULFIDES) WITH ADJUSTABLE MELT VISCOSITY | BAYER AG (DE) | 1992-03-11 | — | — | EP | disclosed |