SCHEMBL1127672

SCHEMBL1127672

O=C(c1ccccc1)c1ccccc1Sc1ccc(-c2ccc(Sc3ccccc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.56
CDC25B P30305 1/20 0.49
ATM Q13315 1/20 0.49
MAPT P10636 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 3/20 0.46
HPGD P15428 1/20 0.46
AKR1C3 P42330 1/20 0.46
LMNA P02545 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
RAB9A P51151 1/20 0.43
GAA P10253 1/20 0.43
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP12 P39900 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2129013 0.92 SIRT1 (0.65) SIRT1CDC25BATMMAPTTDP1
SCHEMBL9625444 0.88 SIRT1 (0.56) SIRT1CDC25BATMMAPTTDP1
SCHEMBL28682830 0.85 SRD5A2 (0.55) SIRT1CDC25BATMMAPTTDP1
SCHEMBL2233495 0.84 AKR1C3 (0.56) SIRT1MAPTTDP1ALDH1A1AKR1C3
SCHEMBL28304795 0.84 SIRT1 (0.51) SIRT1MAPTTDP1ALDH1A1HPGD
SCHEMBL27641577 0.84 SIRT1 (0.56) SIRT1MAPTTDP1ALDH1A1HPGD
SCHEMBL26068031 0.84 SIRT1 (0.51) SIRT1MAPTTDP1ALDH1A1HPGD
Acetophenone SCHEMBL28395442 0.84 ALDH1A1 (0.59) SIRT1MAPTTDP1ALDH1A1HPGD
SCHEMBL17557423 0.83 CDC25B (0.47) SIRT1CDC25BATMMAPTALDH1A1
SCHEMBL21679514 0.83 SIRT1 (0.54) SIRT1CDC25BATMMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118284274-A Charge-transporting varnish 日产化学株式会社 2024-07-02 CN disclosed
US-20240176239-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION FILM, CURED PRODUCT, PREPARATION METHOD OF CURED PRODUCT, HOLLOW STRUCTURE, AND ELECTRONIC COMPONENT TORAY INDUSTRIES, INC. (JP) 2024-05-30 US disclosed
US-20240160105-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN FILM, PHOTOSENSITIVE DRY FILM, AND PATTERN FORMATION METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-16 US disclosed
CN-112470551-B Sealing agent for organic electroluminescent display element 电化株式会社 2024-05-14 CN disclosed
CN-113227159-B Composition and method for producing the same 电化株式会社 2024-04-19 CN disclosed
US-20240059831-A1 CURABLE COMPOSITION AND CURED PRODUCT OF THE SAME, AND WAFER-LEVEL LENS DAICEL CORPORATION (JP) 2024-02-22 US disclosed
EP-4317240-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION FILM, CURED PRODUCT, PREPARATION METHOD OF CURED PRODUCT, HOLLOW STRUCTURE, AND ELECTRONIC COMPONENT Toray Industries, Inc. (JP) 2024-02-07 EP disclosed
CN-117510794-A Composition and method for producing the same 电化株式会社 2024-02-06 CN disclosed
EP-4282895-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN FILM, PHOTOSENSITIVE DRY FILM, AND PATTERN FORMATION METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-29 EP disclosed
CN-113272383-B Composition and method for producing the same 电化株式会社 2023-11-17 CN disclosed
US-8278030-B2 Sulfonium salt, photoacid generator, and photocurable composition and cured body thereof SAN-APRO LIMITED (JP) 2012-10-02 US disclosed
EP-2485290-A1 MATERIAL FOR ORGANIC ELECTRONICS, ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY ELEMENT USING ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATING DEVICE, AND DISPLAY DEVICE Hitachi Chemical Company, Ltd. (JP) 2012-08-08 EP disclosed
US-20120181530-A1 MATERIAL FOR ORGANIC ELECTRONICS, ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY ELEMENT USING ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATING DEVICE, AND DISPLAY DEVICE RESONAC CORPORATION (JP) 2012-07-19 US disclosed
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF SAN-APRO LIMITED (JP) 2011-02-17 US disclosed
EP-2284165-A1 PHOSPHONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION San-Apro Limited (JP) 2011-02-16 EP disclosed
EP-2239295-A2 Radiation-curable silicone composition Shin-Etsu Chemical Co., Ltd. (JP) 2010-10-13 EP disclosed
US-20100255417-A1 RADIATION-CURABLE SILICONE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-10-07 US disclosed
US-7709598-B2 Fluorinated alkyl fluorophoshoric acid salts of onium and transition metal complex SAN-APRO LIMITED (JP) 2010-05-04 US disclosed
US-20070225458-A1 Novel Fluorinated Alkyl Fluorophosphoric Acid Salts of Onium and Ttransition Metal Complex SAN-APRO LIMITED (JP) 2007-09-27 US disclosed
EP-1752463-A1 NOVEL FLUORINATED ALKYLFLUOROPHOSPHORIC ACID SALT OF ONIUM AND TRANSITION METAL COMPLEX San-Apro Limited (JP) 2007-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF ARSA, ASIC1, TST SIRT1 1556/4885CDC25B 3027/4885ATM 928/4885
US-20070225458-A1 Novel Fluorinated Alkyl Fluorophosphoric Acid Salts of Onium and Ttransition Metal Complex AS3MT, TTR, PFAS SIRT1 4238/4885CDC25B 2210/4885ATM 2086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.