Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9625240 | 0.82 | KDM4E (0.39) | KDM4ETAAR1RIPK1ALDH1A1HPGD | |
| Oxalic Acid SCHEMBL9625642 | 0.76 | RIPK1 (0.43) | KDM4ESMN1; SMN2RIPK1TDP1POLB | |
| SCHEMBL5394972 | 0.74 | PPARG (0.49) | KDM4ERIPK1TDP1POLBAPEX1 | |
| SCHEMBL9875291 | 0.74 | FAAH (0.54) | RIPK1HPGD | |
| Oxalic Acid SCHEMBL9625360 | 0.72 | RIPK1 (0.39) | KDM4ERIPK1ALDH1A1TDP1HPGD | |
| Oxalic Acid SCHEMBL9626820 | 0.72 | HPGD (0.38) | KDM4ERIPK1POLBHPGDCTBP2 | |
| Oxalic Acid SCHEMBL9625536 | 0.72 | FFAR1 (0.37) | KDM4ERIPK1ALDH1A1POLBHPGD | |
| SCHEMBL3832104 | 0.71 | KCNN4 (0.48) | KDM4ERIPK1ALDH1A1TDP1POLB | |
| SCHEMBL9626513 | 0.71 | RIPK1 (0.47) | KDM4ESMN1; SMN2RIPK1TDP1POLB | |
| Oxalic Acid SCHEMBL9625351 | 0.70 | TDP1 (0.45) | KDM4ERIPK1ALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322391-B1 | NEW PHENYLALKYLAMINE DERIVATIVES | AKTIEBOLAGET ASTRA (SE) | 1992-03-25 | — | — | EP | disclosed |