Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3832104 | 0.75 | KCNN4 (0.48) | KDM4ERIPK1HPGDTDP1POLB | |
| SCHEMBL9626513 | 0.75 | RIPK1 (0.47) | KDM4ERIPK1HPGDTDP1POLB | |
| SCHEMBL5394972 | 0.75 | PPARG (0.49) | KDM4ERIPK1HPGDTDP1POLB | |
| SCHEMBL9875291 | 0.75 | FAAH (0.54) | RIPK1HPGDGAAMEN1KMT2A | |
| SCHEMBL9625078 | 0.74 | RIPK1 (0.41) | KDM4ERIPK1HPGDTDP1POLB | |
| SCHEMBL14185300 | 0.72 | KDM4E (0.62) | KDM4ERIPK1HPGDTDP1GAA | |
| SCHEMBL5381952 | 0.72 | MMP8 (0.47) | KDM4ERIPK1HPGDTDP1POLB | |
| SCHEMBL28195018 | 0.72 | TDP1 (0.56) | KDM4EHPGDTDP1POLBAPEX1 | |
| SCHEMBL9625307 | 0.72 | VNN1 (0.40) | KDM4ERIPK1HPGDTDP1POLB | |
| Oxalic Acid SCHEMBL9625240 | 0.72 | KDM4E (0.39) | KDM4ERIPK1HPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1023478-C | Novel compounds | ASTRA AB (SE) | 1994-01-12 | — | — | CN | disclosed |
| EP-0322391-B1 | NEW PHENYLALKYLAMINE DERIVATIVES | AKTIEBOLAGET ASTRA (SE) | 1992-03-25 | — | — | EP | disclosed |
| CN-1034710-A | New compound | ASTRA AB (SE) | 1989-08-16 | — | — | CN | disclosed |