Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CA3 | P07451 | 2/20 | 0.56 |
| ▸ | CA5A | P35218 | 2/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Dithiothreitol SCHEMBL8433109 | 0.88 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL12971621 | 0.86 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL13861685 | 0.84 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL8424916 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL27889238 | 0.79 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL1252712 | 0.77 | CA3 (0.86) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL67884 | 0.77 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL733643 | 0.77 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL865063 | 0.77 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL10231803 | 0.77 | CA3 (0.86) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114904012-B | Active oxygen self-supplementing amphiphilic block copolymer-drug conjugate, preparation method and application thereof | 四川大学华西医院 | 2023-12-15 | — | — | CN | claimed |
| CN-115074026-A | Carbon fiber corona roller for lithium battery aluminum foil | 马鞍山欧凯新材料科技有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-114904012-B | Active oxygen self-supplementing amphiphilic block copolymer-drug conjugate, preparation method and application thereof | 四川大学华西医院 | 2023-12-15 | — | — | CN | disclosed |
| WO-2022226252-A1 | HYDROPHILIC POLY(THIOKETAL) URETHANE SCAFFOLDS AND METHODS OF USE THEREOF | VANDERBILT UNIVERSITY (US) | 2022-10-27 | — | — | WO | disclosed |
| CN-115074026-A | Carbon fiber corona roller for lithium battery aluminum foil | 马鞍山欧凯新材料科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-114904012-A | Active oxygen self-complementary amphiphilic block copolymer-drug conjugate, preparation method and application thereof | 四川大学华西医院 | 2022-08-16 | — | — | CN | disclosed |
| US-20210008220-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLYROTAXANES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-01-14 | — | — | US | disclosed |
| EP-2876166-B1 | New compound for sequencing by synthesis | ROCHE DIAGNOSTICS GMBH (DE) | 2016-12-14 | — | — | EP | disclosed |
| US-9410197-B2 | Compound for sequencing by synthesis | ROCHE MOLECULAR SYSTEMS INC. (US) | 2016-08-09 | — | — | US | disclosed |
| EP-2876166-A1 | New compound for sequencing by synthesis | Roche Diagniostics GmbH (DE) | 2015-05-27 | — | — | EP | disclosed |
| US-20150140561-A1 | COMPOUND FOR SEQUENCING BY SYNTHESIS | ROCHE DIAGNOSTICS GMBH (DE) | 2015-05-21 | — | — | US | disclosed |
| US-4988716-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1991-01-29 | — | — | US | disclosed |
| US-4889873-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1989-12-26 | — | — | US | disclosed |
| US-4798842-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |
| US-4758594-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0123543-B1 | LEUKOTRIENE ANTAGONISTS, THEIR PRODUCTION AND USE AND COMPOSITIONS CONTAINING THEM | MERCK FROSST CANADA INC. (CA) | 1988-02-03 | — | — | EP | disclosed |
| US-4696946-A | Topical Treatment of hyperproliferative skin diseases | SCHERING CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |
| US-4609744-A | 4-oxo-benzopyran carboxylic acids | MERCK FROSST CANADA INC. (CA) | 1986-09-02 | — | — | US | disclosed |
| EP-0169033-A2 | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |
| EP-0123543-A1 | Leukotriene antagonists, their production and use and compositions containing them | MERCK FROSST CANADA INC. (CA) | 1984-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210008220-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLYROTAXANES | SI, VIP, TMPRSS15 | ALDH1A1 2803/4885SMN1; SMN2 3228/4885POLB 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.