SCHEMBL9626716

SCHEMBL9626716

COc1ccc(C(=O)C(C)CS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.62
MMP13 P45452 2/20 0.50
MMP1 P03956 1/20 0.50
HTT P42858 2/20 0.49
ALDH1A1 P00352 5/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
RAB9A P51151 3/20 0.48
NPC1 O15118 2/20 0.48
TAS2R14 Q9NYV8 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
MITF O75030 1/20 0.47
LMNA P02545 1/20 0.47
HIF1A Q16665 1/20 0.47
KMT2A Q03164 2/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6550974 0.87 HSD11B1 (0.49) HSD11B1MMP1HTTALDH1A1RAB9A
SCHEMBL31561612 0.77 PPARG (0.57) ALDH1A1SMN1; SMN2RAB9ANPC1CES2
SCHEMBL6203408 0.77 HSD11B1 (1.00) HSD11B1ALDH1A1SMN1; SMN2RAB9ANPC1
SCHEMBL8414713 0.76 POLB (0.47) HSD11B1MMP13KMT2APOLBMEN1
SCHEMBL9218545 0.76 POLB (0.47) HSD11B1MMP13KMT2APOLBMEN1
SCHEMBL28397210 0.75 HSD11B1 (0.61) HSD11B1MMP13MMP1HTTALDH1A1
SCHEMBL28397208 0.75 HSD11B1 (0.61) HSD11B1MMP13MMP1HTTALDH1A1
SCHEMBL28748804 0.75 HSD11B1 (0.61) HSD11B1MMP13MMP1HTTALDH1A1
SCHEMBL7365625 0.75 PSIP1 (0.52) HSD11B1HTTALDH1A1TDP1KMT2A
SCHEMBL29275322 0.74 HSD11B1 (0.74) HSD11B1MMP1HTTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0476865-A1 Resist material and process for forming pattern using the same WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1992-03-25 EP disclosed