Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 10/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 10/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628439 | 0.71 | L3MBTL1 (0.49) | PDE3BPDE3AKDM4EALDH1A1MEN1 | |
| SCHEMBL9628449 | 0.70 | HTR2A (0.41) | CA12CA9CA1CA3CA4 | |
| SCHEMBL9626626 | 0.70 | PDE3B (0.33) | CA12CA9CA1CA3CA4 | |
| SCHEMBL9626996 | 0.65 | KDM4E (0.50) | PDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL9626856 | 0.64 | HPGD (0.50) | CA9CA1PDE3BPDE3AKDM4E | |
| SCHEMBL9626791 | 0.64 | CYP1A2 (0.46) | CA12CA9CA1CA3CA4 | |
| SCHEMBL30752502 | 0.63 | CA12 (0.38) | CA12CA9CA1CA3CA4 | |
| SCHEMBL9096832 | 0.63 | PDE3B (0.38) | CA12CA9CA1CA3CA4 | |
| SCHEMBL13849653 | 0.63 | KDM4E (0.50) | CA12CA9CA1CA3CA4 | |
| SCHEMBL9096470 | 0.63 | HPGD (0.50) | PDE3BPDE3AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093339-A | Anticoagulant, hypotensive, antiangina, antiasthma, antiulcer, anti-platelet activating factor | KODAMA KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0355689-A2 | Pyrano [f] quinoline derivatives and pharmaceutical compositions containing the same | KODAMA KABUSHIKI KAISHA (JP) | 1990-02-28 | — | — | EP | disclosed |