Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 11/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 11/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109246 | 0.78 | HTR1D (0.38) | MTNR1A | |
| SCHEMBL9096470 | 0.77 | HPGD (0.50) | PDE3BPDE3AKDM4E | |
| SCHEMBL9245586 | 0.76 | HTR1A (0.33) | PDE3BPDE3AMTNR1AKDM4EALOX15 | |
| SCHEMBL9626996 | 0.75 | KDM4E (0.50) | PDE3BPDE3AKDM4EHSD17B10 | |
| SCHEMBL9096832 | 0.73 | PDE3B (0.38) | PDE3BPDE3ANQO2CA12CA1 | |
| SCHEMBL9628449 | 0.72 | HTR2A (0.41) | PDE3BPDE3ANQO2CA12CA1 | |
| SCHEMBL9095629 | 0.70 | PDE3B (0.34) | PDE3BPDE3ANQO2CA12CA1 | |
| SCHEMBL9627284 | 0.70 | MAP3K14 (0.42) | PDE3BPDE3ANQO2CA12CA1 | |
| SCHEMBL6091809 | 0.66 | HTR1D (0.44) | — | |
| SCHEMBL9626856 | 0.66 | HPGD (0.50) | PDE3BPDE3ANQO2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093339-A | Anticoagulant, hypotensive, antiangina, antiasthma, antiulcer, anti-platelet activating factor | KODAMA KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0355689-A2 | Pyrano [f] quinoline derivatives and pharmaceutical compositions containing the same | KODAMA KABUSHIKI KAISHA (JP) | 1990-02-28 | — | — | EP | disclosed |