Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628796 | 0.98 | ALDH1A1 (0.35) | ALDH1A1CYP1A2HPGDHSD17B10DRD2 | |
| SCHEMBL19284188 | 0.80 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10KDM4EHTT | |
| SCHEMBL9627804 | 0.79 | KCNH2 (0.41) | ALDH1A1CYP1A2HPGDHSD17B10DRD2 | |
| SCHEMBL9628979 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CYP1A2HPGDHSD17B10DRD2 | |
| SCHEMBL8030664 | 0.73 | DRD2 (0.52) | ALDH1A1CYP1A2HPGDHSD17B10DRD2 | |
| SCHEMBL21022668 | 0.73 | CYP3A4 (0.49) | ALDH1A1CYP1A2HPGDHSD17B10HTT | |
| SCHEMBL9628786 | 0.72 | ALDH1A1 (0.33) | ALDH1A1HPGDKDM4EHTTCA2 | |
| SCHEMBL6741877 | 0.71 | DRD2 (0.53) | DRD2SLC6A4SLC6A3CNR1CNR2 | |
| SCHEMBL11782096 | 0.70 | DRD2 (0.48) | ALDH1A1CYP1A2HPGDHSD17B10DRD2 | |
| SCHEMBL10663196 | 0.70 | ALDH1A1 (0.40) | ALDH1A1CYP1A2HPGDHSD17B10DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203033-B1 | AMINO ETHYL DERIVATIVE OF BENZOTHIAZOLINTHION AS A LUBRICANT ADDITIVE | CIBA-GEIGY AG (CH) | 1992-03-11 | — | — | EP | disclosed |
| US-4810399-A | FRICTION, WEAR, CORROSION AND OXIDATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |
| US-4803001-A | RESISTANT TO FRICTION, WEAR, CORROSION AND OXIDATION | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| US-4737302-A | Aminomethyl derivatives of benzothiazolinethione as lubricant additives | CIBA-GEIGY CORPORATION (US) | 1988-04-12 | — | — | US | disclosed |