Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10877326 | 0.79 | DRD2 (0.35) | — | |
| SCHEMBL9628967 | 0.77 | F12 (0.34) | ALDH1A1KDM4EHPGDKMT2AF12 | |
| SCHEMBL9628527 | 0.72 | ALDH1A1 (0.35) | ALDH1A1CA2CYP3A4KDM4EHPGD | |
| SCHEMBL502087 | 0.69 | CYP4Z1 (0.45) | ALDH1A1CYP3A4KDM4EHPGD | |
| SCHEMBL21022668 | 0.67 | CYP3A4 (0.49) | ALDH1A1CA2CYP3A4HPGDTDP1 | |
| SCHEMBL10756591 | 0.66 | CYP4Z1 (0.41) | ALDH1A1CYP3A4KDM4EHPGDLMNA | |
| SCHEMBL8030664 | 0.66 | DRD2 (0.52) | ALDH1A1HPGDF12 | |
| SCHEMBL28221096 | 0.66 | ALDH1A1 (0.43) | ALDH1A1CA2CYP3A4KDM4EHPGD | |
| SCHEMBL2230293 | 0.64 | TLR8 (0.38) | ALDH1A1KDM4EHPGDKMT2ATSHR | |
| SCHEMBL9628571 | 0.64 | HSD17B10 (0.39) | ALDH1A1KDM4EHPGDKMT2AF12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203033-B1 | AMINO ETHYL DERIVATIVE OF BENZOTHIAZOLINTHION AS A LUBRICANT ADDITIVE | CIBA-GEIGY AG (CH) | 1992-03-11 | — | — | EP | disclosed |
| US-4810399-A | FRICTION, WEAR, CORROSION AND OXIDATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |
| US-4803001-A | RESISTANT TO FRICTION, WEAR, CORROSION AND OXIDATION | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| US-4737302-A | Aminomethyl derivatives of benzothiazolinethione as lubricant additives | CIBA-GEIGY CORPORATION (US) | 1988-04-12 | — | — | US | disclosed |
| EP-0203033-A2 | Amino ethyl derivative of benzothiazolinthion as a lubricant additive | CIBA-GEIGY AG (CH) | 1986-11-26 | — | — | EP | disclosed |