Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627661 | 0.73 | CNR1 (0.34) | HSD17B10ALDH1A1CYP1A2HPGDMEN1 | |
| SCHEMBL9628967 | 0.72 | F12 (0.34) | HSD17B10ALDH1A1CYP1A2HPGDGAA | |
| SCHEMBL9628515 | 0.70 | DRD2 (0.43) | HSD17B10ALDH1A1CYP1A2HPGDMEN1 | |
| SCHEMBL9629848 | 0.69 | RAB9A (0.35) | HSD17B10ALDH1A1CYP1A2HPGDGAA | |
| SCHEMBL13657451 | 0.66 | ALDH1A1 (0.40) | HSD17B10ALDH1A1CYP1A2HPGDGAA | |
| SCHEMBL230331 | 0.66 | F12 (0.59) | ALDH1A1CYP1A2GAAMEN1KMT2A | |
| SCHEMBL11783847 | 0.66 | ALDH1A1 (0.44) | HSD17B10ALDH1A1CYP1A2HPGDGAA | |
| SCHEMBL9628823 | 0.64 | SLC6A4 (0.39) | HSD17B10ALDH1A1CYP1A2HPGDGAA | |
| SCHEMBL19514739 | 0.64 | ALDH1A1 (0.47) | HSD17B10ALDH1A1CYP1A2HPGDGAA | |
| SCHEMBL11780045 | 0.63 | L3MBTL1 (0.65) | HSD17B10ALDH1A1CYP1A2HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203033-B1 | AMINO ETHYL DERIVATIVE OF BENZOTHIAZOLINTHION AS A LUBRICANT ADDITIVE | CIBA-GEIGY AG (CH) | 1992-03-11 | — | — | EP | disclosed |
| US-4810399-A | FRICTION, WEAR, CORROSION AND OXIDATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |
| US-4803001-A | RESISTANT TO FRICTION, WEAR, CORROSION AND OXIDATION | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| US-4737302-A | Aminomethyl derivatives of benzothiazolinethione as lubricant additives | CIBA-GEIGY CORPORATION (US) | 1988-04-12 | — | — | US | disclosed |