Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | FPR1 | P21462 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628571 | 0.70 | HSD17B10 (0.39) | DRD2SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL9628967 | 0.67 | F12 (0.34) | DRD2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL9628523 | 0.66 | DRD2 (0.52) | DRD2SLC6A4SLC6A3ALDH1A1HSD17B10 | |
| SCHEMBL9629848 | 0.64 | RAB9A (0.35) | ALDH1A1RAB9ATSHRCYP3A4POLB | |
| SCHEMBL11983129 | 0.64 | SIGMAR1 (0.39) | DRD2SLC6A4SLC6A3TSHRCYP3A4 | |
| SCHEMBL10604337 | 0.63 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP3A4MEN1POLB | |
| SCHEMBL13657451 | 0.61 | ALDH1A1 (0.40) | DRD2SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL11783847 | 0.60 | ALDH1A1 (0.44) | DRD2SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL9628249 | 0.58 | DRD2 (0.51) | DRD2SLC6A4SLC6A3ALDH1A1HSD17B10 | |
| SCHEMBL29013451 | 0.57 | ALDH1A1 (0.50) | ALDH1A1RAB9ATSHRCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203033-B1 | AMINO ETHYL DERIVATIVE OF BENZOTHIAZOLINTHION AS A LUBRICANT ADDITIVE | CIBA-GEIGY AG (CH) | 1992-03-11 | — | — | EP | disclosed |
| US-4803001-A | RESISTANT TO FRICTION, WEAR, CORROSION AND OXIDATION | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| US-4737302-A | Aminomethyl derivatives of benzothiazolinethione as lubricant additives | CIBA-GEIGY CORPORATION (US) | 1988-04-12 | — | — | US | disclosed |