Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628979 | 0.80 | ALDH1A1 (0.41) | DRD2SLC6A4SLC6A3CYP1A2HPGD | |
| SCHEMBL9629861 | 0.79 | RAB9A (0.40) | DRD2SLC6A4SLC6A3CYP1A2HPGD | |
| SCHEMBL9628803 | 0.74 | ALDH1A1 (0.43) | DRD2SLC6A4SLC6A3CYP1A2HPGD | |
| SCHEMBL9628861 | 0.72 | GAA (0.38) | HPGDALDH1A1HSD17B10TP53GAA | |
| SCHEMBL513869 | 0.71 | ALDH1A1 (0.48) | DRD2SLC6A4SLC6A3CYP1A2HPGD | |
| SCHEMBL9628527 | 0.71 | ALDH1A1 (0.35) | DRD2SLC6A4SLC6A3CYP1A2HPGD | |
| SCHEMBL8030664 | 0.69 | DRD2 (0.52) | DRD2SLC6A4SLC6A3CYP1A2HPGD | |
| SCHEMBL11782096 | 0.69 | DRD2 (0.48) | DRD2SLC6A4SLC6A3CYP1A2HPGD | |
| SCHEMBL9628582 | 0.68 | ALDH1A1 (0.49) | DRD2SLC6A4SLC6A3CYP1A2HPGD | |
| SCHEMBL11776240 | 0.67 | DRD2 (0.53) | DRD2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203033-B1 | AMINO ETHYL DERIVATIVE OF BENZOTHIAZOLINTHION AS A LUBRICANT ADDITIVE | CIBA-GEIGY AG (CH) | 1992-03-11 | — | — | EP | disclosed |
| US-4810399-A | FRICTION, WEAR, CORROSION AND OXIDATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |
| US-4803001-A | RESISTANT TO FRICTION, WEAR, CORROSION AND OXIDATION | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| US-4737302-A | Aminomethyl derivatives of benzothiazolinethione as lubricant additives | CIBA-GEIGY CORPORATION (US) | 1988-04-12 | — | — | US | disclosed |