Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.46 |
| ▸ | CYBB | P04839 | 1/20 | 0.46 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632666 | 0.91 | HDAC1 (0.53) | KIF11NOX1CYBBNOX3NOX4 | |
| SCHEMBL10651353 | 0.82 | KIF11 (0.58) | KIF11NOX1CYBBNOX3NOX4 | |
| SCHEMBL9629595 | 0.81 | HDAC1 (0.48) | HDAC1HDAC8HDAC6MAPTALDH1A1 | |
| SCHEMBL9629602 | 0.78 | KMT2A (0.53) | HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL9629681 | 0.78 | KMT2A (0.49) | NOX1HDAC1HDAC8HDAC6MAPT | |
| SCHEMBL9628766 | 0.74 | MAOA (0.55) | NOX1HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL9628996 | 0.73 | MAPT (0.53) | NOX1HDAC1HDAC8HDAC6MAPT | |
| SCHEMBL30806264 | 0.73 | KIF11 (0.62) | KIF11TDP2 | |
| SCHEMBL4596143 | 0.73 | KIF11 (0.66) | KIF11HDAC1HDAC8HDAC6MAPT | |
| SCHEMBL9024780 | 0.73 | KIF11 (0.67) | KIF11MAPTTDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |