SCHEMBL9629047

SCHEMBL9629047

Fc1ccc(F)c(C(F)(F)F)c1F

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28285438 0.81 KIF11 (0.36) CES2CES1
SCHEMBL15850520 0.81 KIF11 (0.36)
SCHEMBL31576823 0.81
SCHEMBL9693627 0.79 NOTUM (0.43) NOTUM
SCHEMBL20824099 0.79 NOTUM (0.43) NOTUM
SCHEMBL16652774 0.79 KDM1A (0.31)
SCHEMBL8783285 0.79
SCHEMBL20823474 0.79 ACHE (0.33)
SCHEMBL9747729 0.79 ALDH1A1 (0.36) CES2CES1
SCHEMBL17222991 0.79 SOS1 (0.38) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0302326-B1 PROCESS FOR PREPARING FLUORINATED AND OPTIONALLY ALSO CHLORINATED BENZOTRIFLUORIDES, AND BENZOTRIFLUORIDES BAYER AG (DE) 1992-04-15 EP claimed
US-4962246-A INSECTICIDE INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 1990-10-09 US claimed
EP-0302326-A1 Process for preparing fluorinated and optionally also chlorinated benzotrifluorides, and benzotrifluorides BAYER AG (DE) 1989-02-08 EP claimed
WO-2023190846-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING AROMATIC COMPOUND ダイキン工業株式会社 2023-10-05 WO disclosed
EP-0270964-B1 PROCESS FOR OBTAINING SUBSTITUTED FLUOROBENZENES BAYER AG (DE) 1992-07-08 EP disclosed
EP-0302326-B1 PROCESS FOR PREPARING FLUORINATED AND OPTIONALLY ALSO CHLORINATED BENZOTRIFLUORIDES, AND BENZOTRIFLUORIDES BAYER AG (DE) 1992-04-15 EP disclosed
US-4962246-A INSECTICIDE INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 1990-10-09 US disclosed
US-4885415-A HYDROGENATION, DECHLORINATION, CATALYSIS BAYER AKTIENGESELLSCHAFT (DE) 1989-12-05 US disclosed
EP-0302326-A1 Process for preparing fluorinated and optionally also chlorinated benzotrifluorides, and benzotrifluorides BAYER AG (DE) 1989-02-08 EP disclosed
EP-0270964-A2 Process for obtaining substituted fluorobenzenes BAYER AG (DE) 1988-06-15 EP disclosed