Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FER | P16591 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Darenzepine SCHEMBL996265 | 0.76 | MEN1 (0.52) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| Darenzepine SCHEMBL9629094 | 0.76 | MEN1 (0.52) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| Isatin SCHEMBL4625841 | 0.68 | MAOA (0.69) | KMT2AMEN1KDM4EGLAPDGFRA | |
| Isatin SCHEMBL4624064 | 0.66 | MAOA (0.67) | KMT2AMEN1KDM4EGLAPDGFRA | |
| SCHEMBL13243415 | 0.64 | SETD7 (0.57) | KMT2AMEN1KDM4EGLAPDGFRA | |
| SCHEMBL27425410 | 0.64 | LRRK2 (0.74) | KDM4EPDGFRAFERLTKCDK8 | |
| SCHEMBL2420711 | 0.63 | LRRK2 (0.90) | KDM4EPDGFRAFERLTKCDK8 | |
| SCHEMBL366728 | 0.63 | — | — | |
| Isatin SCHEMBL4624395 | 0.63 | MAOA (0.61) | KMT2AMEN1KDM4EGLAPDGFRA | |
| SCHEMBL30681308 | 0.63 | IDO1 (0.57) | KMT2AMEN1KDM4EPDGFRAFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276735-B1 | AQUEOUS OR WATER-DISPERSABLE POWDERY PREPARATION OF A SLIGHTLY WATER SOLUBLE PHARMACEUTICALLY ACTIVE AGENT, AND PROCESS FOR ITS PRODUCTION | BASF Aktiengesellschaft (DE) | 1992-04-01 | — | — | EP | disclosed |