Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Darenzepine SCHEMBL996265 | 1.00 | MEN1 (0.52) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10518957 | 0.85 | KIT (0.48) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL10524643 | 0.79 | NPSR1 (0.46) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5879643 | 0.76 | MAPT (0.63) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL5879640 | 0.76 | MAPT (0.63) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL5879639 | 0.76 | MAPT (0.63) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL9629102 | 0.76 | KMT2A (0.46) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30685721 | 0.73 | MET (0.66) | MEN1KMT2AKITAURKBKDR | |
| SCHEMBL12143508 | 0.72 | MAPT (0.58) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL10517978 | 0.71 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276735-B1 | AQUEOUS OR WATER-DISPERSABLE POWDERY PREPARATION OF A SLIGHTLY WATER SOLUBLE PHARMACEUTICALLY ACTIVE AGENT, AND PROCESS FOR ITS PRODUCTION | BASF Aktiengesellschaft (DE) | 1992-04-01 | — | — | EP | disclosed |