Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.74 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.74 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.74 |
| ▸ | FER | P16591 | 1/20 | 0.74 |
| ▸ | LTK | P29376 | 1/20 | 0.74 |
| ▸ | CDK8 | P49336 | 1/20 | 0.74 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.74 |
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 1/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | CASP2 | P42575 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420711 | 0.90 | LRRK2 (0.90) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL366728 | 0.90 | — | — | |
| SCHEMBL1368292 | 0.85 | LRRK2 (1.00) | LRRK2ACVR1PDGFRAFERLTK | |
| Hydrochloric Acid SCHEMBL6299954 | 0.83 | LRRK2 (0.95) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL11993852 | 0.82 | LRRK2 (0.63) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL28886187 | 0.81 | LRRK2 (0.75) | LRRK2ACVR1PDGFRAFERLTK | |
| Phthalimide SCHEMBL11040503 | 0.81 | GSK3B (1.00) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL181764 | 0.81 | LRRK2 (0.59) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL17816635 | 0.81 | LRRK2 (0.59) | LRRK2ACVR1PDGFRAFERLTK | |
| Phthalimide SCHEMBL64 | 0.81 | GSK3B (1.00) | LRRK2ACVR1PDGFRAFERLTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240224783-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240224783-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD2, OCIAD1, ICOSLG | LRRK2 358/4885ACVR1 3949/4885PDGFRA 2587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.