Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HLA-A | P04439 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629529 | 0.89 | MEN1 (0.37) | MEN1KMT2AMAPTALDH1A1KCNH2 | |
| SCHEMBL9629492 | 0.89 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1KCNH2 | |
| SCHEMBL9630536 | 0.89 | MEN1 (0.42) | MEN1KMT2AMAPTALDH1A1KCNH2 | |
| SCHEMBL9687066 | 0.84 | RET (0.39) | MEN1KMT2AMAPTALDH1A1SSTR5 | |
| SCHEMBL9870928 | 0.83 | MEN1 (0.38) | MEN1KMT2AMAPTALDH1A1KCNH2 | |
| SCHEMBL9629623 | 0.83 | WHR1 (0.39) | MEN1KMT2AMAPTALDH1A1DNMT1 | |
| Oxalic Acid SCHEMBL9630637 | 0.83 | MEN1 (0.42) | MEN1KMT2AMAPTALDH1A1OPRM1 | |
| Oxalic Acid SCHEMBL9630643 | 0.83 | MEN1 (0.42) | MEN1KMT2AMAPTALDH1A1OPRM1 | |
| Oxalic Acid SCHEMBL9687735 | 0.82 | MEN1 (0.42) | MEN1KMT2AMAPTALDH1A1KCNH2 | |
| Oxalic Acid SCHEMBL9687737 | 0.82 | MEN1 (0.42) | MEN1KMT2AMAPTALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151424-A | Antiallergens or antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-09-29 | — | — | US | disclosed |
| EP-0297661-B1 | [(Bicyclic heterocyclyl)methyl and -hetero] substituted hexahydro-1H-azepines and pyrrolidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-09-16 | — | — | EP | disclosed |
| US-5071846-A | Anti-hystaminic [(bicyclic heterocyclyl) methyl and --hetero] substituted hexahydro-1H-azepines and pyrrolidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-12-10 | — | — | US | disclosed |
| US-4988689-A | Antiallergens, antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-01-29 | — | — | US | disclosed |