Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630536 | 0.85 | MEN1 (0.42) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL9629492 | 0.85 | MEN1 (0.41) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| Oxalic Acid SCHEMBL9687644 | 0.84 | KCNH2 (0.47) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| Oxalic Acid SCHEMBL9687648 | 0.84 | KCNH2 (0.47) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL9630174 | 0.83 | MEN1 (0.39) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL9687066 | 0.81 | RET (0.39) | MEN1KMT2AALDH1A1MAPTSSTR5 | |
| Oxalic Acid SCHEMBL9630643 | 0.81 | MEN1 (0.42) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| Oxalic Acid SCHEMBL9630637 | 0.81 | MEN1 (0.42) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| Oxalic Acid SCHEMBL9687735 | 0.80 | MEN1 (0.42) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| Oxalic Acid SCHEMBL9687737 | 0.80 | MEN1 (0.42) | MEN1KMT2AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071846-A | Anti-hystaminic [(bicyclic heterocyclyl) methyl and --hetero] substituted hexahydro-1H-azepines and pyrrolidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-12-10 | — | — | US | claimed |