Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577722 | 0.72 | CHRNB2 (0.44) | CHRNB2CHRNA7CHRNA4CYP2A6ALDH1A1 | |
| SCHEMBL8403545 | 0.70 | POLB (0.61) | POLBTSHRALDH1A1KMT2A | |
| SCHEMBL4573389 | 0.70 | POLB (0.46) | POLBALDH1A1 | |
| SCHEMBL1741490 | 0.70 | SLC6A2 (0.53) | CHRNB2CHRNA7CHRNA4CYP2A6ALDH1A1 | |
| SCHEMBL7151365 | 0.65 | KMT2A (0.67) | POLBL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL10775630 | 0.64 | POLB (0.55) | POLBTDP1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL10131987 | 0.64 | ESR2 (0.56) | POLBCYP2C19GRIA2 | |
| SCHEMBL4455 | 0.62 | CA2 (0.62) | POLBALDH1A1 | |
| SCHEMBL564730 | 0.62 | ALDH1A1 (0.54) | POLBTDP1ALDH1A1KMT2A | |
| SCHEMBL8277240 | 0.62 | CA2 (0.62) | POLBTSHRTDP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153210-A | Hypoglycemic agent, animal growth regulator; veterinary medicine | BEECHAM GROUP P.L.C. (GB) | 1992-10-06 | — | — | US | disclosed |
| EP-0236624-A2 | Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-09-16 | — | — | EP | disclosed |