Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | TERT | O14746 | 6/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701246 | 0.89 | TERT (0.78) | LMNAMAPTTERTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4293444 | 0.81 | TERT (0.95) | LMNAMAPTTERTTP53L3MBTL1 | |
| SCHEMBL23706685 | 0.80 | LMNA (0.59) | LMNAMAPTTERTTP53L3MBTL1 | |
| SCHEMBL29801728 | 0.80 | LMNA (0.59) | LMNAMAPTTERTTP53L3MBTL1 | |
| SCHEMBL5151404 | 0.80 | TP53 (0.74) | LMNAMAPTTERTTP53L3MBTL1 | |
| SCHEMBL8244969 | 0.79 | TP53 (0.72) | LMNAMAPTTERTTP53L3MBTL1 | |
| SCHEMBL6486081 | 0.79 | TP53 (0.72) | LMNAMAPTTERTTP53L3MBTL1 | |
| SCHEMBL13591868 | 0.78 | L3MBTL1 (0.73) | LMNAMAPTTERTTP53L3MBTL1 | |
| SCHEMBL13779305 | 0.78 | ALDH1A1 (1.00) | LMNAMAPTTERTTP53L3MBTL1 | |
| SCHEMBL1356631 | 0.77 | TP53 (0.70) | LMNAMAPTTERTTP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482119-A1 | INTERCALATING AGENTS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1992-04-29 | — | — | EP | claimed |
| WO-1991000265-A1 | INTERCALATING AGENTS | CANCER RESEARCH TECHNOLOGY LTD. (GB) | 1991-01-10 | — | — | WO | claimed |