Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP12 | P39900 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424064 | 0.91 | AGBL2 (0.47) | L3MBTL1AGBL2MMP2MMP9MMP12 | |
| SCHEMBL9005922 | 0.80 | L3MBTL1 (0.36) | L3MBTL1HTTCA2CA4 | |
| SCHEMBL9630994 | 0.80 | HTT (0.42) | L3MBTL1AGBL2MMP2MMP9MMP12 | |
| SCHEMBL7708631 | 0.78 | L3MBTL1 (0.45) | L3MBTL1AGBL2MMP2MMP9MMP12 | |
| SCHEMBL7037491 | 0.77 | AGBL2 (0.46) | L3MBTL1AGBL2MMP2MMP9MMP12 | |
| SCHEMBL9630038 | 0.77 | AGBL2 (0.46) | L3MBTL1AGBL2MMP2MMP9MMP12 | |
| SCHEMBL7030014 | 0.73 | SMN1; SMN2 (0.41) | L3MBTL1MMP2MMP9MMP12HTT | |
| SCHEMBL9631094 | 0.70 | PTGDR2 (0.34) | CYP2C9CYP2C19HPGDLMNASMN1; SMN2 | |
| SCHEMBL9631104 | 0.70 | HPGD (0.38) | L3MBTL1HTTHPGDSMN1; SMN2 | |
| SCHEMBL11577641 | 0.69 | MAPT (0.50) | L3MBTL1AGBL2MMP2MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309626-B1 | PROCESS FOR THE PREPARATION OF DIBENZOTHIEPIN DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-4891433-A | Process for the preparation of dibenzothiepin derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0309626-A1 | Process for the preparation of dibenzothiepin derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |