Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562284 | 0.84 | CYP2C9 (0.54) | L3MBTL1CYP2C9CYP2C19NPSR1CYP1A2 | |
| SCHEMBL7030014 | 0.81 | SMN1; SMN2 (0.41) | L3MBTL1MMP2MMP9MMP12MMP14 | |
| SCHEMBL9630994 | 0.80 | HTT (0.42) | L3MBTL1CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL9630038 | 0.80 | AGBL2 (0.46) | L3MBTL1CYP1A2MMP2MMP9MMP12 | |
| SCHEMBL7037491 | 0.80 | AGBL2 (0.46) | L3MBTL1CYP2C9CYP2C19CYP2D6MMP2 | |
| SCHEMBL9631099 | 0.78 | L3MBTL1 (0.39) | L3MBTL1CYP2C9CYP2C19CYP2D6MMP2 | |
| SCHEMBL28370615 | 0.78 | AGBL2 (0.45) | L3MBTL1CYP2C9CYP2C19NPSR1CYP1A2 | |
| SCHEMBL11707313 | 0.78 | SLC6A4 (0.61) | L3MBTL1CYP2C9CYP2C19NPSR1CYP1A2 | |
| SCHEMBL11577641 | 0.76 | MAPT (0.50) | L3MBTL1CYP2C19CYP1A2CYP3A4MMP2 | |
| SCHEMBL11706477 | 0.76 | ALDH1A1 (0.52) | L3MBTL1CYP2C9CYP2C19NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |