Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631351 | 0.86 | TDP1 (0.44) | TDP1ALDH1A1TAAR1POLBKMT2A | |
| SCHEMBL27563086 | 0.79 | PDE5A (0.43) | PDE5ATDP1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL7783897 | 0.77 | ADRA1A (0.42) | TDP1ALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL5057097 | 0.77 | ADRA1A (0.42) | TDP1ALDH1A1POLBKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8781949 | 0.75 | BLM (0.44) | TDP1ALDH1A1POLBKMT2AKDM4E | |
| Alcohol SCHEMBL4169316 | 0.74 | POLB (0.40) | TDP1ALDH1A1TAAR1POLBKMT2A | |
| SCHEMBL4161041 | 0.72 | LMNA (0.42) | TDP1ALDH1A1TAAR1POLBKMT2A | |
| SCHEMBL4178220 | 0.72 | LMNA (0.42) | TDP1ALDH1A1TAAR1POLBKMT2A | |
| SCHEMBL4169342 | 0.72 | LMNA (0.42) | TDP1ALDH1A1TAAR1POLBKMT2A | |
| SCHEMBL19231144 | 0.71 | ALDH1A1 (0.41) | TDP1ALDH1A1TAAR1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145998-A | Reduction of oxime or silyloxime | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0237305-B1 | A METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0237305-A2 | A method for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-16 | — | — | EP | disclosed |