Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR3 | O15455 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632014 | 0.91 | TLR3 (0.45) | TLR3TLR9TLR8MAPTALDH1A1 | |
| SCHEMBL9632320 | 0.87 | TLR3 (0.41) | TLR3TLR9TLR8MAPTALDH1A1 | |
| SCHEMBL10374647 | 0.81 | TLR3 (0.40) | TLR3TLR9TLR8MAPTALDH1A1 | |
| SCHEMBL9632256 | 0.79 | TLR3 (0.46) | TLR3MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9632121 | 0.78 | ALDH1A1 (0.41) | MAPTALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL9533679 | 0.75 | KCNH2 (0.39) | TLR3MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9531520 | 0.74 | HIF1A (0.46) | TLR3TLR9TLR8MAPTALDH1A1 | |
| SCHEMBL9533583 | 0.71 | TLR3 (0.43) | TLR3TLR9TLR8MAPTALDH1A1 | |
| SCHEMBL9632290 | 0.69 | ALDH1A1 (0.44) | MAPTALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL8490863 | 0.68 | KMT2A (0.39) | MAPTALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |