Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | TLR3 | O15455 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BCL9 | O00512 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490863 | 0.81 | KMT2A (0.39) | KCNH2KMT2AMAPTMAOBPTGS2 | |
| SCHEMBL9632014 | 0.77 | TLR3 (0.45) | KCNH2KMT2AMAPTMAOBTLR3 | |
| SCHEMBL9531441 | 0.77 | PTGS2 (0.42) | KCNH2KMT2AMAPTPTGS2ALDH1A1 | |
| SCHEMBL9531581 | 0.76 | TLR3 (0.41) | KCNH2KMT2AMAPTMAOBTLR3 | |
| SCHEMBL8340736 | 0.75 | PTGS2 (0.39) | KCNH2KMT2AMAPTMAOBPTGS2 | |
| SCHEMBL9530770 | 0.75 | MAPT (0.42) | KMT2AMAPTMAOBALDH1A1POLB | |
| SCHEMBL9631366 | 0.75 | TLR3 (0.42) | KCNH2KMT2AMAPTMAOBTLR3 | |
| SCHEMBL9533583 | 0.72 | TLR3 (0.43) | KCNH2KMT2AMAPTTLR3PTGS2 | |
| SCHEMBL9531520 | 0.71 | HIF1A (0.46) | KMT2AMAPTTLR3PTGS2ALDH1A1 | |
| SCHEMBL7536176 | 0.69 | TTPA (0.51) | KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |