Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.48 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630285 | 0.87 | OPRM1 (0.44) | OPRD1OPRK1OPRM1HTR7MEN1 | |
| SCHEMBL9632061 | 0.86 | OPRD1 (0.50) | OPRD1OPRK1OPRM1HTR7MEN1 | |
| SCHEMBL4563119 | 0.76 | OPRD1 (0.54) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| SCHEMBL9631397 | 0.75 | PTPN1 (0.38) | HTR7MEN1KMT2AKCNA3 | |
| SCHEMBL14282904 | 0.73 | OPRD1 (0.50) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| SCHEMBL11037050 | 0.72 | OPRD1 (0.53) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| SCHEMBL8314872 | 0.72 | OPRD1 (0.55) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| SCHEMBL4693977 | 0.71 | TSHR (0.57) | OPRD1OPRK1SETD7KMT2A | |
| SCHEMBL14198374 | 0.71 | SETD7 (0.58) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| SCHEMBL16481505 | 0.71 | OPRD1 (0.54) | OPRD1OPRK1OPRM1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079249-A | Serotine antagonists at 5-HT2 level, antiallergens, antihistamines | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |
| US-5071847-A | BIS (ARYL) ALKENE COMPOUNDS OF HOMOPIPERIDINES USEFUL AS SEROTONIN-ANTAGONISTS | ADIR ET COMPAGNIE (FR) | 1991-12-10 | — | — | US | disclosed |
| US-5028607-A | Antiserotonine agents | ADIR ET COMPAGNIE (FR) | 1991-07-02 | — | — | US | disclosed |