Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | DGKA | P23743 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630285 | 0.90 | OPRM1 (0.44) | OPRD1OPRM1OPRK1MAPTDGKA | |
| SCHEMBL9631391 | 0.86 | OPRD1 (0.48) | OPRD1OPRM1OPRK1MEN1HTR7 | |
| SCHEMBL16481505 | 0.83 | OPRD1 (0.54) | OPRD1OPRM1OPRK1MAPTDGKA | |
| SCHEMBL10963542 | 0.79 | HTR2A (0.54) | ALDH1A1CYP2D6KDM4EHTR2AHTR2C | |
| SCHEMBL10932484 | 0.78 | MAPT (0.49) | MAPTALDH1A1LMNADRD2DRD4 | |
| SCHEMBL9816191 | 0.77 | DRD2 (0.46) | OPRD1OPRM1OPRK1MAPTDGKA | |
| SCHEMBL9632071 | 0.77 | PTPN1 (0.41) | ALDH1A1TDP1KDM4EDRD2DRD4 | |
| SCHEMBL11541244 | 0.75 | DRD2 (0.65) | OPRM1LMNACYP2D6CYP2C9TSHR | |
| SCHEMBL9073468 | 0.75 | SIGMAR1 (0.55) | LMNACYP2C9KDM4EDRD2HTR1A | |
| SCHEMBL13904313 | 0.75 | DRD2 (0.65) | OPRM1LMNACYP2D6CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079249-A | Serotine antagonists at 5-HT2 level, antiallergens, antihistamines | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |
| US-5071847-A | BIS (ARYL) ALKENE COMPOUNDS OF HOMOPIPERIDINES USEFUL AS SEROTONIN-ANTAGONISTS | ADIR ET COMPAGNIE (FR) | 1991-12-10 | — | — | US | disclosed |
| US-5028607-A | Antiserotonine agents | ADIR ET COMPAGNIE (FR) | 1991-07-02 | — | — | US | disclosed |