SCHEMBL9631487

SCHEMBL9631487

CC1CN(CCC[Si](C)(C)c2ccc(Oc3ccccc3)cc2)CC(C)O1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
GAA P10253 1/20 0.55
KDM4E B2RXH2 7/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 2/20 0.45
POLB P06746 1/20 0.44
TDP1 Q9NUW8 2/20 0.44
MGAM O43451 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41
SIGMAR1 Q99720 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9632634 0.88 KDM4E (0.50) ALDH1A1MEN1KMT2AGAAKDM4E
SCHEMBL9631903 0.86 KDM4E (0.47) ALDH1A1MEN1KMT2AKDM4ELMNA
SCHEMBL9631471 0.80 ALDH1A1 (0.52) ALDH1A1MEN1KMT2AGAAKDM4E
SCHEMBL9632652 0.78 SIGMAR1 (0.65) ALDH1A1KMT2AKDM4ELMNAHTT
SCHEMBL9631134 0.74 SIGMAR1 (0.51) ALDH1A1MEN1KMT2AGAAKDM4E
SCHEMBL9663923 0.73 SIGMAR1 (0.49) ALDH1A1MEN1KMT2AKDM4ELMNA
SCHEMBL9631817 0.73 LMNA (0.44) ALDH1A1MEN1KMT2AGAAKDM4E
SCHEMBL11143216 0.72 NR1H2 (0.50) ALDH1A1KMT2AGAALMNAHTT
SCHEMBL14204986 0.71 KDM4E (0.61) ALDH1A1MEN1KMT2AGAAKDM4E
SCHEMBL9631481 0.71 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0313353-B1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI DOWELANCO (US) 1992-06-17 EP claimed
US-4927812-A FUNGICIDES ATOCHEM NORTH AMERICA, INC. (US) 1990-05-22 US claimed
EP-0313353-B1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI DOWELANCO (US) 1992-06-17 EP disclosed
WO-1989003640-A1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI THE DOW CHEMICAL COMPANY (US) 1989-05-05 WO disclosed
EP-0313353-A1 Morpholinyl silanes and use for control of plant diseases caused by fungi DOWELANCO (US) 1989-04-26 EP disclosed