Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | GPR3 | P46089 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbazole SCHEMBL738564 | 0.80 | PTGS1 (0.47) | ALDH1A1HSD17B10GPR3KDM4ELMNA | |
| Carbazole SCHEMBL7710915 | 0.80 | PTGS1 (0.47) | ALDH1A1HSD17B10GPR3KDM4ELMNA | |
| Carbazole SCHEMBL16345387 | 0.77 | ALDH1A1 (0.64) | ALDH1A1HSD17B10GPR3KDM4ESMN1; SMN2 | |
| Carbazole SCHEMBL742559 | 0.76 | ALDH1A1 (0.70) | ALDH1A1HSD17B10GPR3KDM4ESMN1; SMN2 | |
| Carbazole SCHEMBL10650068 | 0.76 | ALDH1A1 (0.70) | ALDH1A1HSD17B10GPR3KDM4ESMN1; SMN2 | |
| Carbazole SCHEMBL450294 | 0.75 | PTGS1 (0.53) | ALDH1A1HSD17B10GPR3KDM4ELMNA | |
| Carbazole SCHEMBL3393214 | 0.75 | PTGS1 (0.53) | ALDH1A1HSD17B10GPR3KDM4ELMNA | |
| Carbazole SCHEMBL28207216 | 0.74 | PTGS1 (0.52) | ALDH1A1HSD17B10GPR3KDM4ELMNA | |
| SCHEMBL294039 | 0.74 | — | — | |
| SCHEMBL6772032 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051314-A | FROM FUNGUS OF CLASS BASIDIOMYCETES, ANTICANCER AGENTS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1977-09-27 | — | — | US | claimed |
| EP-0353861-B1 | ANGIOGENESIS INHIBITOR | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-05-13 | — | — | EP | disclosed |
| US-4975422-A | PLANT EXTRACT; PROTEIN, POLYSACCHARIDE COMPLEX | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-12-04 | — | — | US | disclosed |
| EP-0353861-A1 | Angiogenesis inhibitor | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-02-07 | — | — | EP | disclosed |
| EP-0295962-A2 | Protein-polysaccharide for treating retroviral infections | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-12-21 | — | — | EP | disclosed |