Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 3/20 | 0.35 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | MC4R | P32245 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631397 | 0.87 | PTPN1 (0.38) | PTPN1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9632061 | 0.77 | OPRD1 (0.50) | CACNA1GALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11037164 | 0.75 | KDM4E (0.43) | ALDH1A1MEN1KMT2AKDM4EDRD3 | |
| SCHEMBL8316992 | 0.75 | HRH3 (0.39) | ALDH1A1MEN1KMT2AKDM4EDRD2 | |
| SCHEMBL10932484 | 0.74 | MAPT (0.49) | ALDH1A1GAADRD2DRD4DRD3 | |
| SCHEMBL11036104 | 0.74 | KDM4E (0.41) | ALDH1A1MEN1KMT2AKDM4EDRD2 | |
| SCHEMBL10559968 | 0.72 | KCNH2 (0.49) | ALDH1A1MEN1KMT2AKDM4EDRD2 | |
| SCHEMBL10963542 | 0.71 | HTR2A (0.54) | ALDH1A1KDM4EHTR7HRH2HRH1 | |
| Oxalic Acid SCHEMBL10558317 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EDRD2 | |
| SCHEMBL9630285 | 0.70 | OPRM1 (0.44) | ALDH1A1MEN1KMT2AKDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079249-A | Serotine antagonists at 5-HT2 level, antiallergens, antihistamines | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |
| US-5028607-A | Antiserotonine agents | ADIR ET COMPAGNIE (FR) | 1991-07-02 | — | — | US | disclosed |